An important feature of systemic
lupus erythematosus and autoimmune diseases in general, is the multiplicity of
symptoms generated. When the compromised immune system becomes confused and
target the blood cells and tissues instead of foreign antigens, the disease can
affect almost every part of the body, produce a variety of symptoms, often
unusual autoimmune diseases groups. Lupus commonly affects the joints, skin,
blood vessels, heart, lungs or even the brain (central nervous system). The
symptoms generally produced by lupus and other similar autoimmune diseases are
non-specific in nature and are frequently misleading in the diagnosis of
disease. Lupus often generates symptoms such as pronounced fatigue, body
weakness, pain, swelling and stiffness in the joints, fever, kidney damage and
rashes.
Medical scientists have not been able to find a cure
for lupus. With proper treatment most patients with lupus can live healthy and
active lives. The progression of lupus is fluctuating and unpredictable,
alternating between periods of disease exacerbation of symptoms and periods of
remission. The term "lupus" encompasses a variety of different types
that can be classified as follows:
Systemic lupus erythematosus (SLE), the most common
type of lupus, has a pronounced polyvalent character. The systemic form of
lupus can affect various parts of the body and cause a wide variety of
non-specific symptoms, ranging from mild to severe. Lupus is considered a
highly problematic disease, being difficult to diagnose and often requiring
treatment being combined.
Induced lupus is a rare form of the disease that occurs as a result of intolerance to drugs. This type of lupus produces symptoms that are very similar to systemic lupus erythematosus: rash, unexplained fever, pulmonary and coronary affections, and arthritis. However, unlike the systemic form of the disease, drug-induced lupus contains no renal impairment and often disappears when the offending drug is administered. The most common drugs that have been identified to cause drug-induced lupus are: hydralazine (Apresoline), methyldopa (Aldomet), procainamide (Procan), isoniazid (INH), quinidine (Quinaglute), phenytoin (Dilantin) and carbamazepine ( Tegretol).
This last type of lupus refers to the neonatal form of the disease. Neonatal lupus is a rare disease that affects newborns of mothers diagnosed with systemic lupus erythematosus or other similar autoimmune diseases. Children affected by this type of lupus often suffer from congenital heart disease and circulatory problems. Sometimes children with neonatal lupus may also suffer from disorders of the liver disease and skin. When the disease is diagnosed, life expectancy in young patients and the general condition can be improved with treatment. Immediate medical intervention is crucial for patients with suspected neonatal lupus.
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