Islet cells contain two types of cells:
The alpha cells that produce glucagon, a hormone that stimulates an increase in the sugar level in the blood, based on the work of insulin, and
Beta cells, the cells responsible for secretion of insulin, the hormone that down-regulates the amount of sugar in the blood.
Pancreas transplantation is a surgical procedure used to replace the old pancreas, non-functional, or just functional, with a new one. Several thousand of these transplants were performed in people with type 1 diabetes have type 2 diabetes are not the usual consideration for this procedure.
What are the indications for a pancreas transplant?
Type 1 diabetics do not respond to conventional treatment. The American Diabetes Association says diabetics who suffer from:
Frequent episodes of acute metabolic and severe episodes as ketoacidosis - potentially deadly increase in incomplete byproducts of fat metabolism,
Hypoglycemia - a decrease in blood sugar, or
Hyperglycemia - sharp increase in sugar levels in the blood,
You should consider getting the pancreas transplant. With a new pancreas, people with type 1 diabetes can expect to need insulin injections ..
Diabetic patients who exhibit reactions to insulin injections. Diabetics who respond to insulin injections are another group of suitable candidates for transplantation of the pancreas. To avoid these complications, a pancreas transplant may be the answer
Constantly increased sugar levels in the blood, even with regular insulin injections. Diabetics who seem to be insensitive to insulin, administered by injection, are also potential candidates for a pancreas transplant. With a new pancreas, blood sugar can be better controlled.
Serious kidney damage secondary to persistently increase sugar levels in the blood. According to the American Diabetes Association, diabetics with severe renal impairment or ESRD who plan to receive kidney transplants are also excellent candidates for a pancreas transplant.
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