Studies have shown that it is possible for systemic lupus erythematosus, which affects the nervous system. The lupus patients may experience confusion, difficulty concentrating, headaches, fatigue, strokes or other signs that show the involvement of the nervous system.
Studies have suggested that nerve tissue can be damaged when antibodies attack the nerve cells and blood vessels. It is known that the nervous system needs a continuous flow of blood is needed to supply oxygen and nutrients to tissues. When this flow of blood is delayed or interrupted, the nerve cells are unable to function normally, and symptoms appear.
Symptoms vary depending on where tissue injury is situated. It's good to know that the nervous system contains three parts. The central nervous system includes the brain and spinal cord, nerve fibers in the peripheral nervous system that are intended to provide the skin and muscles the power needed for sensation and movement, and the third part is the autonomic nervous system has the nerve function devices and regular spine that innervate the internal organs.
Inflammation of the blood vessels of the brain seems 10% of all lupus patients is called the central nervous system, Vasculitis. This disease usually requires hospitalization and high doses of Corticosteroids. Some of the symptoms that appear are high fevers, seizures, psychosis and meningitis-type stiffness of the neck. If it is not aggressively managed, the central nervous system Vasculitis system rapidly progressing to stupor and coma.
People with mild to moderate damage, systemic lupus Erythematosus can experience the cognitive dysfunction. This is a group of symptoms that occur in about 50% of these patients, and we can mention here fatigue, memory loss, feelings of confusion and difficulty expressing thoughts. With a Neuropsychological test or a test called positron emission tomography, these symptoms can be clearly documented. It is known that cognitive dysfunction may come and go on their own, but not optimal treatment is available.
Approximately 20% of patients with systemic lupus erythematosus experience the lupus headache. It is known that almost one third of patients with lupus can have a false positive syphilis test positive Cardiolipin antibodies, or a prolonged clotting time test. This is known as lupus anticoagulants name or Antiphospholipid antibodies.
About 1/9 of lupus patients will develop blood clots in various parts of the body, which is called Antiphospholipid blood clots appear in the nervous system, they can cause a stroke and symptoms of stroke include the painless appearance of neurological deficits without any sign of a sudden active lupus. Appears, it should not be taken with blood thinning medications. As treatment includes anti-depressants, counseling and physical therapy, as appropriate.
It was found that drugs used for the treatment of systemic lupus erythematosus can develop symptoms similar to those of the central nervous system lupus. Psychosis may occur due to anti-malarial drugs at very high doses; headache, dizziness and symptoms of meningitis uncommon similar situations can be caused by non-steroidal anti-inflammatory drugs.
Also, if a patient uses Corticosteroids, may not appear mood swings, psychosis, depression, agitation, confusion, if high doses are taken may appear seizures and medication Antihypertensives may be associated with depression or loss of libido.
One study found that people who have both SLE and Sjogren's syndrome may be predisposed to develop Vasculitis or cognitive dysfunction. Sometimes, circulating proteins in the blood can lead to Cryoglobulinemia or hyperviscosity syndrome.
The Plasmapheresis or filtering the blood can ease these complications. Sometimes, sharp drops in the platelet count may be associated with thrombotic Thrombocytopenic Purpura bleeding. People or for S proteins or protein C may clot, and those with lupus, idiopathic Thrombocytopenic Purpura and kidney failure may bleed.
In the peripheral nervous system lupus system, the involvement of the cranial nerves can cause visual disturbances, drooping eyelid (s), ringing in the ear (s), facial pain and dizziness. Symptoms numbness or tingling in the arms or legs can appear if there is an inflammation of the blood vessels supplying the peripheral nerves.
It can also appear symptoms due to conditions other than lupus and electromyogram and nerve conduction tests are usually helpful to determine if the symptoms are due to another cause. The Corticosteroids are used to treat inflammation of peripheral nerves.
It is important for your doctor to know if you experience symptoms of the nervous system. In patients with cognitive dysfunction, Neuropsychological tests may be useful.
Treatment for lupus nervous system depends on its origin, and can include immunosuppressants, anticoagulants, antibiotics, steroids, anti-depressants, counseling or surgery. It was found that for many people with lupus, nervous system involvement is completely reversible.
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